Domains targeting keyword gene therapy

AGTC is developing cures for rare lung and eye diseases, offering hope to patients with unmet medical needs.

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Meira Gene Therapy is a clinical-stage company developing novel treatments for inherited and acquired genetic disorders.

Cure Sanfilippo, Gene therapy, Get help for Sanfilippo, MPS, MPS III, Rare diseases, lysosomal disease, and Fundraising

Cell & Gene Therapy World is moving to Miami in 2018, hosting over 850 senior executives for three days of strategic partnering and learning. Do you want to be involved in the most comprehensive cell and gene therapy event in the calendar?

Join us October 5-7 for the 2016 Cell & Gene Meeting on the Mesa - a three-day conference aimed at bringing together senior industry executives with leading scientific researchers in the cell and gene therapy sector.

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Learn more about Activase® (Alteplase) for Acute Ischemic Stroke Treatment. Indications Activase (alteplase) is indicated for the treatment of acute ischemic stroke. Exclude intracranial hemorrhage as the primary cause of stroke signs and symptoms prior to initiation of treatment. Initiate treatment as soon as possible but within 3 hours after symptom onset. Activase is indicated for use in acute myocardial infarction (AMI) for the reduction of mortality and reduction of the incidence of heart failure. Limitation of Use: The risk of stroke may outweigh the benefit produced by thrombolytic therapy in patients whose AMI puts them at low risk for death or heart failure. Activase is indicated for the lysis of acute massive pulmonary embolism (PE), defined as: • Acute pulmonary emboli obstructing blood flow to a lobe or multiple lung segments. • Acute pulmonary emboli accompanied by unstable hemodynamics, e.g.,failure to maintain blood pressure without supportive measures. Important Safety Information Contraindications Do not administer Activase to treat acute ischemic stroke in the following situations in which the risk of bleeding is greater than the potential benefit: current intracranial hemorrhage (ICH); subarachnoid hemorrhage; active internal bleeding; recent (within 3months) intracranial or intraspinal surgery or serious head trauma; presence of intracranial conditions that may increase the risk of bleeding; bleeding diathesis; and current severe uncontrolled hypertension. Do not administer Activase to treat acute myocardial infarction or pulmonary embolism in the following situations in which the risk of bleeding is greater than the potential benefit: active internal bleeding; history of recent stroke; recent (within 3months) intracranial or intraspinal surgery or serious head trauma; presence of intracranial conditions that may increase the risk of bleeding; bleeding diathesis; and current severe uncontrolled hypertension. Warnings and Precautions Bleeding Activase can cause significant, sometimes fatal, internal or external bleeding, especially at arterial and venous puncture sites.Avoid intramuscular injections and trauma to the patient. Fatal cases of hemorrhage associated with traumatic intubation in patients administered Activase have been reported. Heparin, aspirin, or Activase may cause bleeding complications; therefore carefully monitor for bleeding. If serious bleeding occurs, terminate the Activase infusion. Orolingual Angioedema Monitor patients during and for several hours after infusion for orolingual angioedema. If angioedema develops, discontinue the Activase infusion and promptly institute appropriate therapy. Cholesterol Embolization Cholesterol embolism, sometimes fatal, has been reported rarely in patients treated with thrombolytic agents. Reembolization of Deep Venous Thrombi during Treatment for Acute Massive Pulmonary Embolism Consider the possible risk of reembolization due to the lysis of underlying deep venous thrombi patients with acute massive PE Coagulation Tests May be Unreliable during Activase Therapy Coagulation tests and/or measures of fibrinolytic activity may be unreliable during Activase therapy. Adverse Reactions The most frequent adverse reaction associated with Activase therapy is bleeding. Allergic‑type reactions, e.g.,anaphylactoid reaction, laryngeal edema, orolingual angioedema, rash, and urticaria have been reported.

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AveXis is focused on developing gene therapy for patients with rare and life-threatening neurological genetic diseases, like spinal muscular atrophy (SMA).

SIRION Biotech offers next generation viral vector technologies for every application: gene therapy, vaccination development, cell modeling tools and more. Read more now!

CCRM supports the development of Regenerative Medicine & enabling tech, with a focus on stem cells, cell & gene therapy, to accelerate the translation of scientific discovery into marketable products.

TrakCel provide a unique solution which enables you to manage cell and gene therapy processes enabling you to get to marketer faster

Arthrogen is a biopharmaceutical company developing local gene therapy for inflammatory diseases.

RegMedNet is the network for the regenerative medicine community: share your stem therapy, research and trials insights; access news, webinars, journals.

Information resource for gene therapy news, clinical trials, guidelines, regulation, literature, databases, background and educational information, scientific research articles, clinical trial databases and more gene therapy information

Insights from the World's Best Medical Minds.Connect With Us to Connect With Them. We are a Digital Health Google LaunchPad Start-up.

Brammer Bio provides a complete range of development, and early phase to commercial GMP manufacturing services for cell and gene therapies

Tocagen believes cancer should be a manageable disease - and that long-term remission or elimination of the disease is possible. Learn about our clinical trials.

Learn about LUXTURNA™ (voretigene neparvovec-rzyl), the first FDA-approved gene therapy for a genetic disease

Pathogenesis of hepatic fibrosis and gene therapy. Molecular pathogenesis of hepatocellular carcinoma. Nanovesicles mediated target delivery of anticancer agents and miRNAs. Combination of conventional and gene therapy for the arrest of brain tumors. Regenerative medicine involving stem cells.

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T cell, lentiviral, retroviral, Adenovirus, CMV, suicide gene, T cell receptor, CAR, skin gene therapy, stem cells

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Cell Therapy News provides free weekly updates of regenerative medicine, highlighting the top cell therapy, gene therapy and immunotherapy findings.

REGENXBIO is leveraging its proprietary NAV® Technology and collaborating with world-class clinical advisors to advance the development of life-changing gene therapy treatments for lysosomal storage disorders and ocular diseases.

HORAMA develops innovative gene therapy products for rare ophthalmic diseases to preserve visual autonomy in affected patients.

VGXI is a cGMP contract manufacturer of DNA plasmids for use in pre-clinical research and human clinical trials of DNA Vaccines and gene therapies.

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Learn more about single-bolus TNKase® (tenecteplase) acute myocardial infarction treatment and the 5-second TNKase® dosing and administration. Indication For use in mortality reduction associated with acute myocardial infarction (AMI). Treatment should be initiated as soon as possible after the onset of AMI symptoms. Important Safety Information TNKase therapy in patients with acute myocardial infarction is contraindicated in the following certain situations (eg, active internal bleeding, history of cerebrovascular accident, known bleeding diathesis, severe uncontrolled hypertension) because of an increased risk of bleeding [See CONTRAINDICATIONS in full prescribing information]. The most common complication encountered during TNKase therapy is bleeding. Should serious bleeding (not controlled by local pressure) occur, any concomitant heparin or antiplatelet agents should be discontinued immediately. In certain conditions (eg, recent major surgery, cerebrovascular disease, hypertension) the risk of TNKase therapy may be increased and should be weighed against the anticipated benefits. [See WARNINGS in full prescribing information]. Cholesterol embolism has been reported rarely in patients treated with all types of thrombolytic agents; the true incidence is unknown. Coronary thrombolysis may result in arrhythmias associated with reperfusion. It is recommended that anti-arrhythmic therapy for bradycardia and/or ventricular irritability be available when TNKase is administered. Please see full Prescribing Information for additional important safety information.

Mila's Miracle Foundation to Stop Batten is dedicated to finding a cure for Batten Disease. By funding groundbreaking gene therapy research, we hope to save Mila's life and the lives of children like her diagnosed with the CLN7 variant of Batten Disease.

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international communication forum in human genetics

Welcome to Eos Neuroscience. We are developing novel treatments for blindness and other serious neurological conditions using optogenetic and gene therapy approaches.

Cell and Gene Therapy Software Platform

Find information for healthcare professionals about Rituxan® (rituximab), the only FDA-approved treatment proven to induce remission in patients with GPA and MPA. INDICATION STATEMENT - Rituxan® (rituximab), in combination with glucocorticoids, is indicated for the treatment of adult patients with Granulomatosis with Polyangiitis (GPA) (Wegener’s Granulomatosis) and Microscopic Polyangiitis (MPA) - Limitations of Use: Rituxan is not recommended for use in patients with severe, active infections BOXED WARNINGS and Additional Important Safety Information BOXED WARNINGS Infusion Reactions: Rituxan administration can result in serious, including fatal, infusion reactions. Deaths within 24 hours of Rituxan infusion have occurred. Approximately 80% of fatal infusion reactions occurred in association with the first infusion. Monitor patients closely. Discontinue Rituxan infusion for severe reactions and provide medical treatment for Grade 3 or 4 infusion reactions. Severe Mucocutaneous Reactions: Severe, including fatal, mucocutaneous reactions can occur in patients receiving Rituxan. Hepatitis B Virus (HBV) Reactivation: HBV reactivation can occur in patients treated with Rituxan, in some cases resulting in fulminant hepatitis, hepatic failure, and death. Screen all patients for HBV infection before treatment initiation, and monitor patients during and after treatment with Rituxan. Discontinue Rituxan and concomitant medications in the event of HBV reactivation. Progressive Multifocal Leukoencephalopathy (PML): PML, including fatal PML, can occur in patients receiving Rituxan. Warnings and Precautions Rituxan administration can also result in additional serious, including fatal, adverse reactions including: - Tumor lysis syndrome (TLS): Administer aggressive intravenous hydration, anti‑hyperuricemic agents, monitor renal function - Infections: Withhold Rituxan and institute appropriate anti-infective therapy - Cardiac arrhythmias and angina: Discontinue infusions in case of serious or life-threatening events - Bowel obstruction and perforation: Consider and evaluate for abdominal pain, vomiting, or related symptoms - Live virus vaccines: Do not administer live virus vaccines prior to or during Rituxan - Cytopenias: Monitor blood counts at regular intervals Granulomatosis With Polyangiitis (GPA) (Wegener’s Granulomatosis) and Microscopic Polyangiitis (MPA) - Use of concomitant immunosuppressants other than corticosteroids has not been studied in GPA or MPA patients exhibiting peripheral B-cell depletion following treatment with Rituxan. Observe patients with GPA and MPA closely for signs of infection if immunosuppressants other than corticosteroids are used concomitantly - The safety and efficacy of retreatment with Rituxan have not been established in patients with GPA and MPA - Common adverse reactions (≥15%) in the clinical study were infections, nausea, diarrhea, headache, muscle spasms, anemia, and peripheral edema. Other important adverse reactions include infusion reactions You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555. For additional safety information, please see the Rituxan full prescribing information, including BOXED WARNINGS.

FinVector is a world leader in the research and development of Viral-Based Gene Therapy products, with state-of-the-art facilities and a highly experienced scientific team working in the gene therapy market.

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Dedicated to facilitating education, communication and the sharing of knowledge and expertise

Questions about gene and cell therapy can be directed to [email protected].

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Bringing hope and relief to patients with undertreated rare diseases through the development and commercialization of curative first-in-class gene-modified cell therapies.